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APLP-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32814

Novus Biologicals, part of Bio-Techne
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NBP1-32814

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Chimpanzee (99%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human APLP-2. The exact sequence is proprietary.

Reactivity Notes

Rat (89%), Chicken (83%).

Localization

Cell membrane, Single-pass type I membrane protein , Nucleus , Cell membrane , Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for APLP-2 Antibody

Western Blot: APLP-2 Antibody [NBP1-32814]

Western Blot: APLP-2 Antibody [NBP1-32814]

Western Blot: APLP-2 Antibody [NBP1-32814] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with APLP2 antibody [N1N2], N-term diluted at 1:1000.
Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-32814]

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-32814]

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-32814] - Mouse fore brain dilution: 1:500. Antigen Retrieval: TrilogyTM (EDTA based) buffer, 15min
Western Blot: APLP-2 Antibody [NBP1-32814]

Western Blot: APLP-2 Antibody [NBP1-32814]

Western Blot: APLP-2 Antibody [NBP1-32814] - 50 ug mouse brain lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.

Applications for APLP-2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: APLP-2

APLP2, also known as Amyloid-like protein 2, consists of a 763 amino acid isoform that is 87 kDa, and is involved in hemostasis regulation and neuromuscular transmission regulation. Current research is being conducted on the relationship between APLP2 and several diseases and disorders, such as spinocerebellar ataxia, lissencephaly, cholesterol, pancreatitis, neuroblastoma, infertility, thrombosis, breast cancer, neuronitis, brain disease, dementia, and thrombosis. APLP2 interacts with JUN, APLP1, ZNF512B, DEDD, and ETS1 on homeostasis and behavior pathways.

Long Name

Amyloid Beta [A4] Precursor-like Protein 2

Alternate Names

APLP2, APPH, APPL2, CDEBP, WALPLP2, YWK-II

Gene Symbol

APLP2

Additional APLP-2 Products

Product Documents for APLP-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for APLP-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.