APLP-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89029

Novus Biologicals, part of Bio-Techne
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NBP1-89029
NBP1-89029-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all APLP-2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEDTQPELYHPMK

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 25586139).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for APLP-2 Antibody

Immunocytochemistry/ Immunofluorescence: APLP-2 Antibody [NBP1-89029]

Immunocytochemistry/ Immunofluorescence: APLP-2 Antibody [NBP1-89029]

Immunocytochemistry/Immunofluorescence: APLP-2 Antibody [NBP1-89029] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-89029]

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-89029]

Immunohistochemistry-Paraffin: APLP-2 Antibody [NBP1-89029] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
APLP-2 Antibody

Flow Cytometry: Rabbit Polyclonal APLP-2 Antibody [NBP1-89029] -

Flow Cytometry: Rabbit Polyclonal APLP-2 Antibody [NBP1-89029] - U937 cells were surface stained with 2ug/mL APLP-2 antibody (orange) and matched isotype control (blue) for 30 minutes at 4 degrees Celsius prior to secondary antibody stain. Isotype control and secondary antibodies were conjugated to FITC. Image from a verified customer review.

Applications for APLP-2 Antibody

Application
Recommended Usage

Flow Cytometry

Validated for Flow Cytometry from a verified customer review

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

Reported in scientific literature (PMID: 25586139)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Reviewed Applications

Read 1 review rated 5 using NBP1-89029 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APLP-2

APLP2, also known as Amyloid-like protein 2, consists of a 763 amino acid isoform that is 87 kDa, and is involved in hemostasis regulation and neuromuscular transmission regulation. Current research is being conducted on the relationship between APLP2 and several diseases and disorders, such as spinocerebellar ataxia, lissencephaly, cholesterol, pancreatitis, neuroblastoma, infertility, thrombosis, breast cancer, neuronitis, brain disease, dementia, and thrombosis. APLP2 interacts with JUN, APLP1, ZNF512B, DEDD, and ETS1 on homeostasis and behavior pathways.

Long Name

Amyloid Beta [A4] Precursor-like Protein 2

Alternate Names

APLP2, APPH, APPL2, CDEBP, WALPLP2, YWK-II

Entrez Gene IDs

334 (Human)

Gene Symbol

APLP2

UniProt

Q06481

Additional APLP-2 Products

Product Documents for APLP-2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APLP-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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