Apolipoprotein E/ApoE Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41216

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Apolipoprotein E/ApoE Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E. The immunogen is located within amino acids 220 - 270 of APO-E. Amino Acid Squence: ARMEEMGSRTRDRLDEVKE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Apolipoprotein E/ApoE Antibody - BSA Free

Western Blot: Apolipoprotein E/ApoE AntibodyBSA Free [NBP2-41216]

Western Blot: Apolipoprotein E/ApoE AntibodyBSA Free [NBP2-41216]

Western Blot: Apolipoprotein E/ApoE Antibody [NBP2-41216] - Western blot analysis of APO-E in human brain tissue lysate with APO-E antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: Apolipoprotein E/ApoE Antibody - BSA Free [NBP2-41216]

Immunocytochemistry/ Immunofluorescence: Apolipoprotein E/ApoE Antibody - BSA Free [NBP2-41216]

Immunocytochemistry/Immunofluorescence: Apolipoprotein E/ApoE Antibody [NBP2-41216] - Staining of APO E in mouse brain tissue with APO E Antibodyat 20 ug/mL.
Immunohistochemistry: Apolipoprotein E/ApoE Antibody - BSA Free [NBP2-41216]

Immunohistochemistry: Apolipoprotein E/ApoE Antibody - BSA Free [NBP2-41216]

Immunohistochemistry: Apolipoprotein E/ApoE Antibody [NBP2-41216] - Staining of APO E in mouse brain tissue with APO E Antibodyat 5 ug/mL.
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Applications for Apolipoprotein E/ApoE Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/mL

Immunohistochemistry-Paraffin

5 ug/mL

Western Blot

1 - 2 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Apolipoprotein E/ApoE

Apolipoprotein E (APOE) is an apolipoprotein located in chylomicrons and intermediate-density lipoproteins that is necessary for the normal catabolism of triglyceride-rich lipoprotein constituents in the liver. APOE has recently been shown to be involseveral biological processes other than lipoprotein transport, including cognition and immunoregulation.

Lipoproteins are responsible for carrying cholesterol and other fats through the bloodstream as little packages and are essential for the normal breakdown of these molecules. In particular, apolipoprotein E is a major component of specific lipoproteins called very low-density lipoproteins (VLDL). A major function of VLDLs is to remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes.

The three Apo E isoforms are strongly associated with cardiovascular disease and Alzheimer's disease, so ApoE antibodies have become useful tools for research in both of these areas.

Alternate Names

APOE

Gene Symbol

APOE

Additional Apolipoprotein E/ApoE Products

Product Documents for Apolipoprotein E/ApoE Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Apolipoprotein E/ApoE Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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