APP Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76910

Novus Biologicals, part of Bio-Techne
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NBP1-76910
NBP1-76910-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat

Predicted:

Guinea Pig (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Dot Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Cytometric Bead Assay Standard, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all APP Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid peptide near the carboxy terminus of human APP. The immunogen is located within the last 50 amino acids of APP. Amino Acid Squence: GYENPTYKFFEQMQN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for APP Antibody - BSA Free

Western Blot: APP AntibodyBSA Free [NBP1-76910]

Western Blot: APP AntibodyBSA Free [NBP1-76910]

Western Blot: APP Antibody [NBP1-76910] - Analysis of APP in mouse brain tissue lysate with APP antibody at (A) 0.5 and (B) 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: APP Antibody - BSA Free [NBP1-76910]

Immunocytochemistry/ Immunofluorescence: APP Antibody - BSA Free [NBP1-76910]

Immunocytochemistry/Immunofluorescence: APP Antibody [NBP1-76910] - Staining of APP in mouse brain tissue with APP Antibodyat 20 ug/mL.
Immunohistochemistry-Paraffin: APP Antibody - BSA Free [NBP1-76910]

Immunohistochemistry-Paraffin: APP Antibody - BSA Free [NBP1-76910]

Immunohistochemistry-Paraffin: APP Antibody [NBP1-76910] - Staining of APP in mouse brain tissue with at 5 ug/mL.
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Applications for APP Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL.

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

0.5-1 ug/ml
Application Notes
Use in Dot Blot reported in scientific literature (PMID:32732283)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: APP

Alzheimer's disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (A 4) protein has been found to be the principal constituent of senile plaques of AD's patients (1-2). The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4 kDa A 4 protein. Two variants of A 4 can be detected; A 1-40 "short-tailed" and A 1-42 "long-tailed" (3-4).

Long Name

Amyloid Precursor Protein

Alternate Names

Amyloid beta, beta Amyloid, Protease Nexin II

Entrez Gene IDs

351 (Human)

Gene Symbol

APP

UniProt

P05067

Additional APP Products

Product Documents for APP Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for APP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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