APRIL/TNFSF13 Antibody (Sacha-2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97600

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # Sacha-2

Format

BSA Free

Concentration

1.0 mg/ml

View all APRIL/TNFSF13 Antibodies »

Product Specifications

Immunogen

Recombinant human APRIL (aa 105-250) fused to human ACRP30headless (aa 16-108).

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for APRIL/TNFSF13 Antibody (Sacha-2) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Immunocytochemistry/ Immunofluorescence

1:10-1:2000
Application Notes
This antibody is useful in ELISA (capture), Flow Cytometry and Immunocytochemistry.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: APRIL/TNFSF13

TNFSF13 is a proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Long Name

A Proliferation-inducing Ligand

Alternate Names

CD256, TALL2, TNFSF13, TRDL1, ZTNF2

Gene Symbol

TNFSF13

Additional APRIL/TNFSF13 Products

Product Documents for APRIL/TNFSF13 Antibody (Sacha-2) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APRIL/TNFSF13 Antibody (Sacha-2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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