APRIL/TNFSF13 Antibody (SR1578)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22069

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22069-100ul
NBP3-22069-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1578

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all APRIL/TNFSF13 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human APRIL/TNFSF13 (Uniprot #: O75888)

Specificity

Detects endogenous levels of total APRIL/TNFSF13

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for APRIL/TNFSF13 Antibody (SR1578)

Western Blot: APRIL/TNFSF13 Antibody (SR1578) [NBP3-22069] -

Western Blot: APRIL/TNFSF13 Antibody (SR1578) [NBP3-22069] - Western blot analysis using NBP3-22069 in Jurkat cell lysate.

Applications for APRIL/TNFSF13 Antibody (SR1578)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APRIL/TNFSF13

TNFSF13 is a proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Long Name

A Proliferation-inducing Ligand

Alternate Names

CD256, TALL2, TNFSF13, TRDL1, ZTNF2

Gene Symbol

TNFSF13

Additional APRIL/TNFSF13 Products

Product Documents for APRIL/TNFSF13 Antibody (SR1578)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for APRIL/TNFSF13 Antibody (SR1578)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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