APXL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13308

Novus Biologicals, part of Bio-Techne
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NBP2-13308
NBP2-13308-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all APXL Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: PPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for APXL Antibody

Immunocytochemistry/ Immunofluorescence: APXL Antibody [NBP2-13308]

Immunocytochemistry/ Immunofluorescence: APXL Antibody [NBP2-13308]

Immunocytochemistry/Immunofluorescence: APXL Antibody [NBP2-13308] - Immunofluorescent staining of human cell line MCF7 shows localization to cell junctions.
Immunohistochemistry-Paraffin: APXL Antibody [NBP2-13308]

Immunohistochemistry-Paraffin: APXL Antibody [NBP2-13308]

Immunohistochemistry-Paraffin: APXL Antibody [NBP2-13308] - Staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.

Applications for APXL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APXL

The protein encoded by the APXL gene shares significant similarities with the apical protein from Xenopus laevis which isimplicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinismtype 1 syndrome. (provided by RefSeq)

Alternate Names

apical protein, Xenopus laevis-like, apical protein-like (Xenopus laevis), Apical-like protein, APX homolog of Xenopus, APXLHSAPXL, DKFZp781J074, FLJ39277, Protein APXL, protein Shroom2, shroom family member 2

Entrez Gene IDs

357 (Human)

Gene Symbol

SHROOM2

UniProt

Q13796 (Human)

Additional APXL Products

Product Documents for APXL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for APXL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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