ARFGAP3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15443

Novus Biologicals, part of Bio-Techne
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NBP2-15443
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (97%), Rhesus Macaque (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARFGAP3 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ARFGAP3. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (97%), Bovine (84%).

Localization

Cytoplasm; Golgi apparatus membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ARFGAP3 Antibody

Western Blot: ARFGAP3 Antibody [NBP2-15443]

Western Blot: ARFGAP3 Antibody [NBP2-15443]

Western Blot: ARFGAP3 Antibody [NBP2-15443] - Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: ARFGAP3 Antibody [NBP2-15443]

Immunohistochemistry-Paraffin: ARFGAP3 Antibody [NBP2-15443]

Immunohistochemistry-Paraffin: ARFGAP3 Antibody [NBP2-15443] - Paraffin-embedded Breast ca, using antibody at 1:500 dilution.

Applications for ARFGAP3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ARFGAP3

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]

Alternate Names

ADP-ribosylation factor GTPase activating protein 1, ADP-ribosylation factor GTPase activating protein 3, ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3, ARFGAP1, FLJ45618

Gene Symbol

ARFGAP3

UniProt

Q9NP61 (Human)

Additional ARFGAP3 Products

Product Documents for ARFGAP3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARFGAP3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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