ARFGEF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84447

Novus Biologicals, part of Bio-Techne
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NBP2-84447-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all ARFGEF2 Antibodies »

Product Summary for ARFGEF2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ARFGEF2. Peptide sequence: SDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKT The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ARFGEF2 Antibody

Western Blot: ARFGEF2 Antibody [NBP2-84447]

Western Blot: ARFGEF2 Antibody [NBP2-84447]

Western Blot: ARFGEF2 Antibody [NBP2-84447] - Host: Rabbit. Target Name: ARFGEF1. Sample Type: Fetal Liver lysates. Antibody Dilution: 1.0ug/ml

Applications for ARFGEF2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARFGEF2

BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles.

Alternate Names

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited), ARFGEP2, BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2, Brefeldin A-inhibited GEP 2, dJ1164I10.1, FLJ23723, PVNH2

Gene Symbol

ARFGEF2

Additional ARFGEF2 Products

Product Documents for ARFGEF2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ARFGEF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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