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ARHGEF4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87037

Novus Biologicals, part of Bio-Techne
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NBP2-87037

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse ARHGEF4. Peptide sequence: ADDYEAPRAGAREADDSGPEAQSCKDQMRTNVINEILSTERDYIKHLRDI The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ARHGEF4 Antibody

Western Blot: ARHGEF4 Antibody [NBP2-87037]

Western Blot: ARHGEF4 Antibody [NBP2-87037]

Western Blot: ARHGEF4 Antibody [NBP2-87037] - Host: Rabbit. Target Name: Arhgef4. Sample Type: Mouse Testis lysates. Antibody Dilution: 1.0ug/ml

Applications for ARHGEF4 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARHGEF4

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through Gucleotide exchange protein coupled receptors. Acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. This protein is similar to rat collybistin protein. Alternative splicing of the gene generates two transcript variants which encode different isoforms.

Alternate Names

APC-stimulated guanine nucleotide exchange factor 1, Asef, ASEF1, ASEFAPC-stimulated guanine nucleotide exchange factor, GEF4, KIAA1112, Rho guanine nucleotide exchange factor (GEF) 4, rho guanine nucleotide exchange factor 4, STM6

Gene Symbol

ARHGEF4

Additional ARHGEF4 Products

Product Documents for ARHGEF4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ARHGEF4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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