ARHGEF6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25284

Novus Biologicals, part of Bio-Techne
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NBP3-25284
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARHGEF6 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein ARHGEF6 using the following amino acid sequence: GSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARHGEF6 Antibody

ARHGEF6 Antibody Immunocytochemistry/Immunofluorescence: ARHGEF6 Antibody [NBP3-25284]

Immunocytochemistry/Immunofluorescence: ARHGEF6 Antibody [NBP3-25284]

Staining of human cell line JURKAT shows localization to plasma membrane & cytosol.

Applications for ARHGEF6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARHGEF6

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq]

Alternate Names

alphaPIX, Alpha-Pix, COOL-2, COOL2alpha, KIAA0006Cool2, mental retardation, X-linked 46, MRX46, PAK-interacting exchange factor alpha, PIXA, Rac/Cdc42 guanine exchange factor (GEF) 6, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, Rac/Cdc42 guanine nucleotide exchange factor 6, rho guanine nucleotide exchange factor 6

Gene Symbol

ARHGEF6

Additional ARHGEF6 Products

Product Documents for ARHGEF6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARHGEF6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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