ARMER Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77198

Novus Biologicals, part of Bio-Techne
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NBP1-77198
NBP1-77198-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ARMER Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER. The immunogen is located within the last 50 amino acids of ARMER. Amino Acid Squence: KREINKLLKQKEKKNE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARMER Antibody - BSA Free

Western Blot: ARMER AntibodyBSA Free [NBP1-77198]

Western Blot: ARMER AntibodyBSA Free [NBP1-77198]

Western Blot: ARMER Antibody [NBP1-77198] - Analysis of ARMER in human bladder cell lysates with anti-ARMER (CT) using NBP1-77198 at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Immunohistochemistry-Paraffin: ARMER Antibody - BSA Free [NBP1-77198]

Immunohistochemistry-Paraffin: ARMER Antibody - BSA Free [NBP1-77198]

Immunohistochemistry-Paraffin: ARMER Antibody [NBP1-77198] - Staining of Human bladder tissue at 2 ug/ml.

Immunocytochemistry/Immunofluorescence: ARMER Antibody [NBP1-77198] -

Immunocytochemistry/Immunofluorescence: ARMER Antibody [NBP1-77198] - Immunofluorescence of ARMER in Mouse Intestine cells with ARMER antibody at 2 ug/mL.
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Applications for ARMER Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2 ug/mL

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

0.5-2 ug/ml

Reviewed Applications

Read 1 review rated 5 using NBP1-77198 in the following applications:

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARMER

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity, although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Alternate Names

ADP-ribosylation factor-like 6 interacting protein, ADP-ribosylation factor-like 6 interacting protein 1, AIP1, Aip-1, apoptotic regulator in the membrane of the endoplasmic reticulum, ARL-6-interacting protein 1, ARL6IPaip-1, ARMER, KIAA0069ADP-ribosylation factor-like protein 6-interacting protein 1

Gene Symbol

ARL6IP1

UniProt

Q15041 (Human)

Additional ARMER Products

Product Documents for ARMER Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ARMER Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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