ARS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15473

Novus Biologicals, part of Bio-Techne
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NBP2-15473
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARS2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human ARS2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (81%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

101 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ARS2 Antibody

Western Blot: ARS2 Antibody [NBP2-15473]

Western Blot: ARS2 Antibody [NBP2-15473]

Western Blot: ARS2 Antibody [NBP2-15473] - A. 30 ug 293T whole cell lysate/extract B. 30 ug A431 whole cell lysate/extractC. 30 ug HeLa whole cell lysate/extract D. 30 ug HepG2 whole cell lysate/extract7.5 % SDS-PAGE ARS2 antibody dilution: 1:1000
Immunocytochemistry/ Immunofluorescence: ARS2 Antibody [NBP2-15473]

Immunocytochemistry/ Immunofluorescence: ARS2 Antibody [NBP2-15473]

Immunocytochemistry/Immunofluorescence: ARS2 Antibody [NBP2-15473] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: ARS2 Antibody [NBP2-15473]

Immunohistochemistry-Paraffin: ARS2 Antibody [NBP2-15473]

Immunohistochemistry-Paraffin: ARS2 Antibody [NBP2-15473] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:500 dilution.

Applications for ARS2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ARS2

Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

Alternate Names

ARS2serrate, arsenate resistance protein 2, arsenate resistance protein ARS2, arsenite resistance protein, Arsenite-resistance protein 2, ASR2, MGC126427, serrate RNA effector molecule homolog, serrate RNA effector molecule homolog (Arabidopsis)

Gene Symbol

SRRT

UniProt

Q9BXP5 (Human)

Additional ARS2 Products

Product Documents for ARS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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