Artemin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-68857

Novus Biologicals, part of Bio-Techne
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NBP1-68857
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Artemin Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-NSTWRTVDRLS corresponding to internal region according to NP_476501.1, NP_476431.2.

Epitope

C-NSTWRTVDRLS

Specificity

This antibody is expected to recognize all reported isoforms (NP_003967.2; NP_476501.1; NP_476431.2). Reported variants represent identical protein: NP_476431.2, NP_001129687.1 Reported variants represent identical protein: NP_003967.2, NP_476432.2

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Artemin Antibody

Western Blot: Artemin Antibody [NBP1-68857]

Western Blot: Artemin Antibody [NBP1-68857]

Western Blot: Artemin Antibody [NBP1-68857] - (0.1ug/ml) staining of HEK293 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Artemin Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 28 kDa band observed in lysates of HEK293, HepG2 and Kelly (PMID: 20118197).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Artemin

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenrative disease. Artemin has been shown in culture to support the survival of a number of periferal neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Four alternatively spliced transcripts have been described, two of which encode the same protein.

Alternate Names

ARTN, Enovin, EVN, Neublastin

Entrez Gene IDs

9048 (Human); 11876 (Mouse); 362572 (Rat)

Gene Symbol

ARTN

Additional Artemin Products

Product Documents for Artemin Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Artemin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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