ASGPR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85581

Novus Biologicals, part of Bio-Techne
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NBP1-85581
NBP1-85581-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ASGR1/ASGPR1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRL

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 23979840).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ASGPR1 Antibody

Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581]

Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581]

Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581] - Staining in human liver and endometrium tissues using NBP1-85581 antibody. Corresponding ASGR1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581]

Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581]

Immunohistochemistry-Paraffin: ASGPR1 Antibody [NBP1-85581] - Staining of human endometrium, kidney, liver and tonsil using Anti-ASGR1 antibody NBP1-85581 (A) shows similar protein distribution across tissues to independent antibody NBP1-85580 (B).
Western Blot: ASGPR1 Antibody [NBP1-85581]

Western Blot: ASGPR1 Antibody [NBP1-85581]

Western Blot: ASGPR1 Antibody [NBP1-85581] - Analysis in human cell line HepG2.
View 5 more images

Applications for ASGPR1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04 - 0.4 ug/ml
Application Notes
IHC reported in scientific literature (PMID: 23979840). For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ASGR1/ASGPR1

Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specificallyremoved from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated(galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubulesto an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to thecell surface and the ligand is transported to the lysosomes for degradation. (provided by RefSeq)

Long Name

Asialoglycoprotein Receptor 1

Alternate Names

ASGPR1, CLEC4H1, MHL1, RHL1

Gene Symbol

ASGR1

Additional ASGR1/ASGPR1 Products

Product Documents for ASGPR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ASGPR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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