Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI2A12

Concentration

1 mg/ml

View all ASGR2 Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human ASGR2 (NP_001172) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Human ASGR2 over-expressing cells. Western blot image submitted by a verified customer review.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Carcinoma of Human liver tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.
Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505]

Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Asialoglycoprotein receptor 2.
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Applications for Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:4000

Reviewed Applications

Read 1 review rated 5 using NBP2-45505 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1% BSA, 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ASGR2

Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.

Long Name

Asialoglycoprotein Receptor 2

Alternate Names

ASGPR2, CLEC4H2, HBXBP

Gene Symbol

ASGR2

Additional ASGR2 Products

Product Documents for Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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