ATG10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24594

Novus Biologicals, part of Bio-Techne
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NBP2-24594
NBP2-24594SS
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all ATG10 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 1-50 of human APG10L was used as the immunogen.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ATG10 Antibody

Western Blot: ATG10 Antibody [NBP2-24594]

Western Blot: ATG10 Antibody [NBP2-24594]

Western Blot: ATG10 Antibody [NBP2-24594] - Analysis of APG10L in human brain lysate in the 1) absence and 2) presence of immunizing peptide 3) mouse brain and 4) rat brain using NBP2-24594 at 2.0 ug/ml, 6.0 ug/ml and 4.0 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: ATG10 Antibody [NBP2-24594]

Immunohistochemistry-Paraffin: ATG10 Antibody [NBP2-24594]

Immunohistochemistry-Paraffin: ATG10 Antibody [NBP2-24594] - Atg10 Antibody [NBP2-24594] - Staining of APG10L in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Applications for ATG10 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

2.0-6.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATG10

Atg10 is a major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. APG10 interacts with LC3A to facilitate the conjugation of ATG12 to ATG5. APG10 is also able to directly interact either with ATG5 or ATG7A. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies.

Long Name

Autophagy Related 10 Homolog

Alternate Names

APG10, APG10L, PP12616

Gene Symbol

ATG10

UniProt

Q9H0Y0

Additional ATG10 Products

Product Documents for ATG10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ATG10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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