ATG12 Antibody (S08-2F4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15002

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15002-100ul
NBP3-15002-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2F4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ATG12 Antibodies »

Product Summary for ATG12 Antibody (S08-2F4)

Immunogen

A synthetic peptide of human ATG12 (Uniprot#: O94817)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ATG12 Antibody (S08-2F4)

Western Blot: ATG12 Antibody (S08-2F4) [NBP3-15002]

Western Blot: ATG12 Antibody (S08-2F4) [NBP3-15002]

Western Blot: ATG12 Antibody (S08-2F4) [NBP3-15002] - Western blot detection of ATG12 in K562, 3T3, Hela cell lysates using ATG12 Rabbit mAb (1:1000 diluted). Predicted band size: 15kDa. Observed band size: 55kDa.

Applications for ATG12 Antibody (S08-2F4)

Application
Recommended Usage

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATG12

The ATG12 gene codes a ubiquitin-like protein ATG12 that in isoform 1 is 140 amino acids long at 15 kDA and in isoform 2 is 74 amino acids long at 7 kDA. This protein is critical for autophagy (bulk protein degradation) as it is the human homolog of a yeast protein that participates in autophagy. ATG12 participates in the immune system, apoptosis and autophagy, protein stability, negative regulators of RIG-I/MDA5 signaling, and glucose/energy metabolism. It is known to interact with various genes such as HIST1H2BF, HIST1H2BE, HIST1H2BI, HIST1H2BG, and HIST1H2BC. ATG12 has been researched regarding its role in leukemia, lung cancer, myositis, retinitis, carcinoma, colorectal cancer, and myelodysplastic syndrome.

Long Name

ATG12 Autophagy Related 12 Homolog

Alternate Names

APG12, FBR93, HAPG12

Gene Symbol

ATG12

Additional ATG12 Products

Product Documents for ATG12 Antibody (S08-2F4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ATG12 Antibody (S08-2F4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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