ATG4C Antibody (S08-8G9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15003

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15003-100ul
NBP3-15003-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-8G9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ATG4C Antibodies »

Product Summary for ATG4C Antibody (S08-8G9)

Immunogen

Recombinant protein of human ATG4C (Uniprot#: Q96DT6)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ATG4C Antibody (S08-8G9)

Western Blot: ATG4C Antibody (S08-8G9) [NBP3-15003]

Western Blot: ATG4C Antibody (S08-8G9) [NBP3-15003]

Western Blot: ATG4C Antibody (S08-8G9) [NBP3-15003] - Western blot detection of ATG4C in K562, Hela cell lysates using ATG4C Rabbit mAb (1:1000 diluted). Predicted band size: 53kDa. Observed band size: 53kDa.
Immunohistochemistry-Paraffin: ATG4C Antibody (S08-8G9) [NBP3-15003]

Immunohistochemistry-Paraffin: ATG4C Antibody (S08-8G9) [NBP3-15003]

Immunohistochemistry-Paraffin: ATG4C Antibody (S08-8G9) [NBP3-15003] - Immunohistochemistry of ATG4C in paraffin-embedded Human lung cancer tissue using ATG4C Rabbit mAb at dilution 1/50

Applications for ATG4C Antibody (S08-8G9)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATG4C

ATG4C is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Alternate Names

APG4 autophagy 4 homolog C, APG4 autophagy 4 homolog C (S. cerevisiae), APG4C, ATG4 autophagy related 4 homolog C (S. cerevisiae), AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteineendopeptidase (S. cerevisiae), AUTL1, AUTL3APG4-C, AUT-like 1, cysteine endopeptidase, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, cysteine protease ATG4C, EC 3.4.22, EC 3.4.22.-, FLJ14867

Gene Symbol

ATG4C

Additional ATG4C Products

Product Documents for ATG4C Antibody (S08-8G9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ATG4C Antibody (S08-8G9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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