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ATIC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32221

Novus Biologicals, part of Bio-Techne
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NBP1-32221

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ATIC. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ATIC Antibody

Western Blot: ATIC Antibody [NBP1-32221]

Western Blot: ATIC Antibody [NBP1-32221]

Western Blot: ATIC Antibody [NBP1-32221] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE ATIC antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: ATIC Antibody [NBP1-32221]

Immunocytochemistry/ Immunofluorescence: ATIC Antibody [NBP1-32221]

Immunocytochemistry/Immunofluorescence: ATIC Antibody [NBP1-32221] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: ATIC Antibody [NBP1-32221]

Immunohistochemistry-Paraffin: ATIC Antibody [NBP1-32221]

Immunohistochemistry-Paraffin: ATIC Antibody [NBP1-32221] - Paraffin-embedded Colon ca, using antibody at 1:100 dilution.

Applications for ATIC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ATIC

ATIC is a 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591 amino acid protein that is 81% identical to the chicken sequence.

Alternate Names

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMPcyclohydrolase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotidetransformylase/inosinicase, AICAR, AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme, AICARFT, AICARFT/IMPCHASE, bifunctional purine biosynthesis protein PURH, IMPCHASE, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase, PURHFLJ93545

Gene Symbol

ATIC

Additional ATIC Products

Product Documents for ATIC Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ATIC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.