Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Long Name

Azurocidin/Cationic Antimicrobial Protein-37/Heparin Binding Protein

Alternate Names

AZAMP, AZU1, CAP37, HBP

Gene Symbol

AZU1

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Product Specific Notices for Azurocidin/CAP37/HBP Antibody (MM0099-7F31) [DyLight 594]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Azurocidin/CAP37/HBP Antibody (MM0099-7F31) [DyLight 594]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12045DL594

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Background: Azurocidin/CAP37/HBP