Azurocidin/CAP37/HBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31613

Novus Biologicals, part of Bio-Techne
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NBP2-31613
NBP2-31613-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Azurocidin/CAP37/HBP Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: FPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Azurocidin/CAP37/HBP Antibody

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613] - Staining in human bone marrow and cerebral cortex tissues using anti-AZU1 antibody. Corresponding AZU1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613]

Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP2-31613] - Staining of human bone marrow shows high expression.

Applications for Azurocidin/CAP37/HBP Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Azurocidin/CAP37/HBP

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Long Name

Azurocidin/Cationic Antimicrobial Protein-37/Heparin Binding Protein

Alternate Names

AZAMP, AZU1, CAP37, HBP

Gene Symbol

AZU1

UniProt

P20160

Additional Azurocidin/CAP37/HBP Products

Product Documents for Azurocidin/CAP37/HBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Azurocidin/CAP37/HBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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