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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCCIP Antibody - BSA Free

Immunohistochemistry: BCCIP Antibody [NBP1-22994]

Immunohistochemistry: BCCIP Antibody [NBP1-22994]

Immunohistochemistry: BCCIP Antibody [NBP1-22994] - FPE section of human colon carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994]

Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994]

Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml).
Immunoprecipitation: BCCIP Antibody [NBP1-22994]

Immunoprecipitation: BCCIP Antibody [NBP1-22994]

Immunoprecipitation: BCCIP Antibody [NBP1-22994] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BCCIP antibody used for IP at 3 mcg/mg lysate. BCCIP was also immunoprecipitated by rabbit anti- BCCIP antibody NBP1-22993, which recognizes an upstream epitope.

Applications for BCCIP Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
It is not recommended for western analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: BCCIP

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Alternate Names

BCCIPalpha, BRCA2 and CDKN1A interacting protein, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, cdk inhibitor p21 binding protein, P21- and CDK-associated protein 1, Protein TOK-1, TOK-1, TOK-1alpha, TOK1BCCIPbeta, TOK-1beta

Entrez Gene IDs

56647 (Human)

Gene Symbol

BCCIP

Additional BCCIP Products

Product Documents for BCCIP Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BCCIP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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