Bcl-2 related protein A1 Antibody (SR2933)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27722

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27722-100ul
NBP3-27722-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2933

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Bcl-2 related protein A1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Bcl-2 related protein A1 (Uniprot #: Q16548)

Specificity

Detects endogenous levels of Bcl-2 related protein A1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Bcl-2 related protein A1 Antibody (SR2933)

Western Blot: Bcl-2 related protein A1 Antibody (SR2933) [NBP3-27722] -

Western Blot: Bcl-2 related protein A1 Antibody (SR2933) [NBP3-27722] - Western blot analysis of Raji cell lysate.

Applications for Bcl-2 related protein A1 Antibody (SR2933)

Application
Recommended Usage

Flow Cytometry

1:100

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Bcl-2 related protein A1

Bcl-2 related protein A1; also known as Bcl2A1 and Bfl1, is an anti-apoptotic Bcl-2 family member preferentially expressed in hematopoietic and endothelial cells (1). Bfl1 is involved in a variety of cellular activities such as embryonic development, homeostatis and tumorigenesis. Expression of Bfl1 is stimulated by NF-kB in response to inflammatory stimuli and is up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40 and phorbol ester (2-3). Blf1 has also been shown to reduce the release of pro-apoptotic cytochrome c from the mitochondria, block caspase activation and suppress apoptosis induced by p53 (4-5).

Alternate Names

BCL2A1, Bcl2L5, Bfl-1, GRS

Gene Symbol

BCL2A1

Additional Bcl-2 related protein A1 Products

Product Documents for Bcl-2 related protein A1 Antibody (SR2933)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Bcl-2 related protein A1 Antibody (SR2933)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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