BCL2L10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88681

Novus Biologicals, part of Bio-Techne
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NBP1-88681
NBP1-88681-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BCL2L10 Antibodies »

Product Summary for BCL2L10 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MVDQLRERTTMADPLRERTELLLADYLGYCARE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCL2L10 Antibody

Immunohistochemistry: BCL2L10 Antibody [NBP1-88681]

Immunohistochemistry: BCL2L10 Antibody [NBP1-88681]

Immunohistochemistry: BCL2L10 Antibody [NBP1-88681] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Applications for BCL2L10 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BCL2L10

The protein encoded by the BCL2L10 gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. (provided by RefSeq)

Long Name

Bcl-2-like protein 10

Alternate Names

BCL-B, Bcl2-L-10, BCLB, BOO, DIVA

Gene Symbol

BCL2L10

Additional BCL2L10 Products

Product Documents for BCL2L10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BCL2L10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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