beta-2 Adrenergic R/ADRB2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90227

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-90227
NBP1-90227-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all beta-2 Adrenergic R/ADRB2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta-2 Adrenergic R/ADRB2 Antibody

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227] - Staining of human skeletal muscle shows very weak membranous positivity in myocytes.
Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]

Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227] - Staining of human prostate shows moderate membranous positivity in glandular cells.
View 1 more images

Applications for beta-2 Adrenergic R/ADRB2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-2 Adrenergic R/ADRB2

The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues. Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver. The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity. Agonists of ADRB2 are most widely used for the treatment of asthma. In complex with beta-arrestin-1 and c-src, the beta-2 adrenergic receptor activates MAP kinases ERK1(MAPK3) and ERK2 (MAPK1). Expression of the beta-2 adrenoceptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. ESTs have been isolated from breast, liver, liver/spleen, placenta, and uterus libraries.

Long Name

Beta-2 Adrenergic Receptor

Alternate Names

ADRB2, ADRB2R, B2AR, beta-2 AdrenergicR, beta2 AdrenergicR

Gene Symbol

ADRB2

Additional beta-2 Adrenergic R/ADRB2 Products

Product Documents for beta-2 Adrenergic R/ADRB2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for beta-2 Adrenergic R/ADRB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.