beta-Arrestin 2 Antibody (4D2)

Novus Biologicals, part of Bio-Techne | Catalog # H00000409-M06

Novus Biologicals, part of Bio-Techne
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H00000409-M06
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4D2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all beta-Arrestin 2 Antibodies »

Product Specifications

Immunogen

ARRB2 (AAH07427, 300 a.a. ~ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC

Reactivity Notes

Rat cross-reactivity determined by WB. Mouse reported in scientific literature (PMID: 21131397).

Specificity

ARRB2 - arrestin, beta 2 (4D2)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for beta-Arrestin 2 Antibody (4D2)

Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06] - Analysis of ARRB2 expression in MCF-7.
Immunocytochemistry/ Immunofluorescence: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Immunocytochemistry/ Immunofluorescence: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Immunocytochemistry/Immunofluorescence: beta-Arrestin 2 Antibody (4D2) [H00000409-M06] - Analysis of monoclonal antibody to ARRB2 on HeLa cell. Antibody concentration 10 ug/ml
Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06]

Western Blot: beta-Arrestin 2 Antibody (4D2) [H00000409-M06] - ARRB2 monoclonal antibody (M06), clone 4D2 Western Blot analysis of ARRB2 expression in HeLa ( Cat # L013V1 ).
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Applications for beta-Arrestin 2 Antibody (4D2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:2000

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: beta-Arrestin 2

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Alternate Names

ARB2, ARR2, ARRB2, betaArrestin 2

Entrez Gene IDs

409 (Human)

Gene Symbol

ARRB2

UniProt

AAH07427 (Human)

Additional beta-Arrestin 2 Products

Product Documents for beta-Arrestin 2 Antibody (4D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for beta-Arrestin 2 Antibody (4D2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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