beta COP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-53091

Novus Biologicals, part of Bio-Techne
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NBP1-53091
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all beta COP Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to COPB1(coatomer protein complex, subunit beta 1) The peptide sequence was selected from the middle region of COPB1. Peptide sequence QLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCS. The peptide sequence for this immunogen was taken from within the described region.

Specificity

This product is specific to Subunit or Isoform: beta.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

107 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for beta COP Antibody

Western Blot: beta COP Antibody [NBP1-53091]

Western Blot: beta COP Antibody [NBP1-53091]

Western Blot: beta COP Antibody [NBP1-53091] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

Applications for beta COP Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta COP

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Alternate Names

beta coat protein, Beta-coat protein, Beta-COP, coatomer protein complex, subunit beta, coatomer protein complex, subunit beta 1, coatomer subunit beta, COPBFLJ57957, DKFZp761K102, FLJ10341, FLJ46444

Entrez Gene IDs

1315 (Human)

Gene Symbol

COPB1

UniProt

P53618 (Human)

Additional beta COP Products

Product Documents for beta COP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for beta COP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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