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beta-Galactosidase-1/GLB1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49602

Novus Biologicals, part of Bio-Techne
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NBP2-49602
NBP2-49602-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for beta-Galactosidase-1/GLB1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta-Galactosidase-1/GLB1 Antibody

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining in human epididymis and skeletal muscle tissues using anti-GLB1 antibody. Corresponding GLB1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602]

Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining of human epididymis shows high expression.

Applications for beta-Galactosidase-1/GLB1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-Galactosidase-1/GLB1

The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Beta-galactosidase also occurs in a complex with neuraminidase (NEU1; MIM 608272) and protective protein/cathepsin A (PPCA; MIM 256540), which is a component of certain cell surface receptors (Hinek, 1996 [PubMed 8922281]). See also galactosylceramidase (GALC; MIM 606890) (EC 3.2.1.46), a genetically distinct beta-galactosidase that is involved in the catabolism of other lipid compounds.[supplied by OMIM]

Alternate Names

betaGalactosidase1, EBP, ELNR1, GLB1, Lactase

Gene Symbol

GLB1

Additional beta-Galactosidase-1/GLB1 Products

Product Documents for beta-Galactosidase-1/GLB1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for beta-Galactosidase-1/GLB1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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