beta ureidopropionase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89918

Novus Biologicals, part of Bio-Techne
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NBP1-89918
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all beta ureidopropionase Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta ureidopropionase Antibody

Western Blot: beta ureidopropionase Antibody [NBP1-89918]

Western Blot: beta ureidopropionase Antibody [NBP1-89918]

Western Blot: beta ureidopropionase Antibody [NBP1-89918] - Analysis in control (vector only transfected HEK293T lysate) and UPB1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918]

Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918]

Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918] - Staining in human liver and colon tissues using anti-UPB1 antibody. Corresponding UPB1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918]

Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918]

Immunohistochemistry-Paraffin: beta ureidopropionase Antibody [NBP1-89918] - Staining of human colon shows low expression as expected.
View 1 more images

Applications for beta ureidopropionase Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta ureidopropionase

beta ureidopropionase encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq]

Alternate Names

Beta-alanine synthase, beta-ureidopropionase, BUP-1, BUP1EC 3.5.1.6, N-carbamoyl-beta-alanine amidohydrolase, ureidopropionase, beta

Gene Symbol

UPB1

Additional beta ureidopropionase Products

Product Documents for beta ureidopropionase Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for beta ureidopropionase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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