BICD1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76922

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all BICD1 Antibodies »

Product Summary for BICD1 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BICD1. The immunogen is located within the last 50 amino acids of BICD1. Amino Acid Squence: CPTVSPDTALPEEQPHS

Specificity

At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BICD1 Antibody - BSA Free

Western Blot: BICD1 AntibodyBSA Free [NBP1-76922]

Western Blot: BICD1 AntibodyBSA Free [NBP1-76922]

Western Blot: BICD1 Antibody [NBP1-76922] - Daudi cell lysate with BICD1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: BICD1 Antibody - BSA Free [NBP1-76922]

Immunocytochemistry/ Immunofluorescence: BICD1 Antibody - BSA Free [NBP1-76922]

Immunocytochemistry/Immunofluorescence: BICD1 Antibody [NBP1-76922] - Immunofluorescence of BICD1 in Daudi cells with BICD1 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: BICD1 Antibody - BSA Free [NBP1-76922]

Immunocytochemistry/ Immunofluorescence: BICD1 Antibody - BSA Free [NBP1-76922]

Immunocytochemistry/Immunofluorescence: BICD1 Antibody [NBP1-76922] - Daudi cells with BICD1 antibody at 2.5 ug/ml.

Applications for BICD1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5-10 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BICD1

BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.

Alternate Names

Bicaudal D (Drosophila) homolog 1, bicaudal D homolog 1 (Drosophila), BICD, Bic-D 1, cytoskeleton-like bicaudal D protein homolog 1, protein bicaudal D homolog 1

Gene Symbol

BICD1

UniProt

NP_001705 (Human)

Additional BICD1 Products

Product Documents for BICD1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BICD1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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