BMP-1/PCP Antibody (OTI3E9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46579

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3E9

Concentration

1 mg/ml

View all BMP-1/PCP Antibodies »

Product Summary for BMP-1/PCP Antibody (OTI3E9)

Immunogen

Human recombinant protein fragment corresponding to amino acids 225-617 of human BMP1(NP_001190) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

80.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMP-1/PCP Antibody (OTI3E9)

Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BMP1.
Immunocytochemistry/ Immunofluorescence: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Immunocytochemistry/ Immunofluorescence: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Immunocytochemistry/Immunofluorescence: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY BMP1.
Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579]

Western Blot: BMP-1/PCP Antibody (OTI3E9) [NBP2-46579] - Analysis of extracts (35ug) from 9 different cell lines. (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Applications for BMP-1/PCP Antibody (OTI3E9)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:4000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BMP-1/PCP

Bone morphogenetic protein 1 (BMP1) is a 986 amino acid member of the bone morphogenetic protein (BMP) family. It was initially discovered for its role to induce cartilage and bone formation. It is a metalloprotease that cleaves the C-terminus of procollagen I, II and III while other BMPs are part of the TGF beta superfamily. It may play a role in herniation, congestive heart failure, breast cancer, myelofibrosis with myeloid metaplasia and infection by HIV-1.

Long Name

Bone Morphogenetic Protein 1

Alternate Names

BMP1, PCP

Gene Symbol

BMP1

Additional BMP-1/PCP Products

Product Documents for BMP-1/PCP Antibody (OTI3E9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BMP-1/PCP Antibody (OTI3E9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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