BMPR-IA/ALK-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15601

Novus Biologicals, part of Bio-Techne
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NBP2-15601
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (98%), Canine (99%), Chicken (95%), Mouse (99%), Porcine (100%), Rat (98%), Rhesus Macaque (100%), Sheep (99%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BMPR-IA/ALK-3 Antibodies »

Product Summary for BMPR-IA/ALK-3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human BMPR-IA/ALK-3. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (86%).

Localization

Membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMPR-IA/ALK-3 Antibody

Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601]

Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601]

Western Blot: BMPR-IA/ALK-3 Antibody [NBP2-15601] - A. 40 ug 293T whole cell lysate/extract. B. 40 ug HepG2 whole cell lysate/extract. C. 15 ug whole cell lysate/extract of human BMPR1A-transfected 293T cells.

Applications for BMPR-IA/ALK-3 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BMPR-IA/ALK-3

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]

Long Name

Bone Morphogenetic Protein Receptor IA/Activin Receptor-like Kinase 3

Alternate Names

ALK-3, BMPR1A, BMPRIA, CD292

Gene Symbol

BMPR1A

UniProt

P36894

Additional BMPR-IA/ALK-3 Products

Product Documents for BMPR-IA/ALK-3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BMPR-IA/ALK-3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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