BMPR-IB/ALK-6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14889

Novus Biologicals, part of Bio-Techne
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NBP2-14889
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine

Predicted:

Canine (98%), Chicken (96%), Porcine (98%), Rhesus Macaque (99%), Sheep (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BMPR-IB/ALK-6 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human BMPR-IB/ALK-6. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMPR-IB/ALK-6 Antibody

Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with BMPR1B antibody [N3C3] diluted at 1:1000.
Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody [NBP2-14889] - Paraffin-embedded human hepatoma. BMPR1B antibody [N3C3] dilution: 1:500.
Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889]

Western Blot: BMPR-IB/ALK-6 Antibody [NBP2-14889] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with BMPR1B antibody diluted at 1:1000.
View 3 more images

Applications for BMPR-IB/ALK-6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Frozen

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BMPR-IB/ALK-6

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq]

Long Name

Bone Morphogenetic Protein Receptor IB

Alternate Names

ALK-6, BMPR1B, BMPRIB, CDw293

Gene Symbol

BMPR1B

UniProt

O00238

Additional BMPR-IB/ALK-6 Products

Product Documents for BMPR-IB/ALK-6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BMPR-IB/ALK-6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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