BNP Antibody (8D5B4C11) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-47507

Novus Biologicals, part of Bio-Techne
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NBP1-47507
NBP1-47507-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 8D5B4C11

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all BNP Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for BNP Antibody (8D5B4C11) - BSA Free

Immunohistochemistry-Paraffin: BNP Antibody (8D5B4C11) - BSA Free [NBP1-47507]

Immunohistochemistry-Paraffin: BNP Antibody (8D5B4C11) - BSA Free [NBP1-47507]

Immunohistochemistry-Paraffin: proBNP Antibody (8D5B4C11) [NBP1-47507] - Analysis of human normal myocardium, showing cytoplasmic localization using BNP1 mouse mAb with DAB staining.

Applications for BNP Antibody (8D5B4C11) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:1000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BNP

Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides, see fig. 18). BNP is a 32 amino acid peptide with disulfide bond between the cystein residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity

Long Name

Brain Natriuretic Peptide

Alternate Names

BNF, NPPB

Entrez Gene IDs

4879 (Human)

Gene Symbol

NPPB

Additional BNP Products

Product Documents for BNP Antibody (8D5B4C11) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BNP Antibody (8D5B4C11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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