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BPNT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32152

Novus Biologicals, part of Bio-Techne
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NBP1-32152

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (93%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (83%), Xenopus laevis (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BPNT1 Antibody

Western Blot: BPNT1 Antibody [NBP1-32152]

Western Blot: BPNT1 Antibody [NBP1-32152]

Western Blot: BPNT1 Antibody [NBP1-32152] - Sample (30ug whole cell lysate)A:HeLa S3 10% SDS PAGE, antibody diluted at 1:500.
Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP1-32152]

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP1-32152]

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP1-32152] - Paraffin-embedded mouse pancreas. BPNT1 antibody [N1C3] dilution: 1:500.
Western Blot: BPNT1 Antibody [NBP1-32152]

Western Blot: BPNT1 Antibody [NBP1-32152]

Western Blot: BPNT1 Antibody [NBP1-32152] - Sample (50 ug of whole cell lysate) A: Mouse liver 12% SDS PAGE; antibody diluted at 1:1000.

Applications for BPNT1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BPNT1

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Alternate Names

3'(2'), 5'-bisphosphate nucleotidase 1,3'(2')5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, BPntase, EC 3.1.3, EC 3.1.3.7, PAP-inositol-1,4-phosphatase, PIP

Gene Symbol

BPNT1

Additional BPNT1 Products

Product Documents for BPNT1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BPNT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.