BPTF/FALZ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84756

Novus Biologicals, part of Bio-Techne
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NBP1-84756
NBP1-84756-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BPTF/FALZ Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BPTF/FALZ Antibody

Immunocytochemistry/ Immunofluorescence: BPTF/FALZ Antibody [NBP1-84756]

Immunocytochemistry/ Immunofluorescence: BPTF/FALZ Antibody [NBP1-84756]

Immunocytochemistry/Immunofluorescence: BPTF/FALZ Antibody [NBP1-84756] - Staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756]

Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756]

Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756] - Staining of human skeletal muscle shows weak to moderate positivity in myocytes.
Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756]

Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756]

Immunohistochemistry-Paraffin: BPTF/FALZ Antibody [NBP1-84756] - Staining of human adrenal gland shows moderate cytoplasmic positivity in glandular cells.
View 3 more images

Applications for BPTF/FALZ Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BPTF/FALZ

FALZ/BPTF is a histone-binding component of NURF (nucleosome remodeling factor), a complex that catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. This gene was identified in brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), containing a DNA-binding domain, a zinc finger motif, and a C-terminal bromodomain, suggested it might play a role in the regulation of transcription during proliferation. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. This protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex.

Long Name

Nucleosome-remodeling factor subunit BPTF

Alternate Names

BPTF, FAC1, FALZ

Gene Symbol

BPTF

Additional BPTF/FALZ Products

Product Documents for BPTF/FALZ Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BPTF/FALZ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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