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BRE Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99253

Novus Biologicals, part of Bio-Techne
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NBP2-99253-100ul
NBP2-99253-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for BRE Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human BRE.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for BRE Antibody

Immunocytochemistry/ Immunofluorescence: BRE Antibody [NBP2-99253]

Immunocytochemistry/ Immunofluorescence: BRE Antibody [NBP2-99253]

Immunocytochemistry/Immunofluorescence: BRE Antibody [NBP2-99253] - Immunofluorescence staining of BRE in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human BRE polyclonal antibody (dilution ratio 1:500) at 4C overnight. Then cells were stained with the Alexa Fluor$488-conjugated Goat Anti-rabbit IgG Secondary antibody (green). Positive staining was localized to cytoplasm and nucleus.
Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253]

Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253]

Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253] - Immunochemical staining BRE in rat brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253]

Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253]

Immunohistochemistry-Paraffin: BRE Antibody [NBP2-99253] - Immunochemical staining BRE in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Applications for BRE Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Immunohistochemistry-Paraffin

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BRE

BRE is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRC

Alternate Names

brain and reproductive organ-expressed (TNFRSF1A modulator), BRCA1/BRCA2-containing complex subunit 45, subunit 4

Gene Symbol

BABAM2

Additional BRE Products

Product Documents for BRE Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BRE Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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