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BRIP1/FANCJ Antibody (SR1035)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22189

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-22189-100ul
NBP3-22189-50ul

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1035

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human BRIP1/FANCJ (Uniprot #: Q9BX63)

Specificity

Detects endogenous levels of total BRIP1/FANCJ

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BRIP1/FANCJ Antibody (SR1035)

Western Blot: BRIP1/FANCJ Antibody (SR1035) [NBP3-22189] -

Western Blot: BRIP1/FANCJ Antibody (SR1035) [NBP3-22189] - Western blot analysis using NBP3-22189 in HeLa cell lysate.

Applications for BRIP1/FANCJ Antibody (SR1035)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BRIP1/FANCJ

The Fanconi anemia group subunit J protein (FANCJ), also called BRIP1 or BACH1, is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. Defects in FANCJ cause the autosomal recessive disorder, Fanconi anemia. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.

FANCG antibodies are useful for DNA repair studies and cell cycle research.

Long Name

BRCA1 Interacting Protein C-terminal Helicase 1

Alternate Names

BACH1, FACJ, FANCJ

Gene Symbol

BRIP1

Additional BRIP1/FANCJ Products

Product Documents for BRIP1/FANCJ Antibody (SR1035)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BRIP1/FANCJ Antibody (SR1035)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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