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BTLA/CD272 Antibody (HMBT-6B2) [Alexa Fluor® 594]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81118AF594

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-81118AF594

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Block/Neutralize, ELISA, Flow Cytometry, Functional, Immunoblotting, Immunoprecipitation, Western Blot

Label

Alexa Fluor 594 (Excitation = 590 nm, Emission = 617 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # HMBT-6B2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for BTLA/CD272 Antibody (HMBT-6B2) [Alexa Fluor® 594]

Immunogen

This antibody was raised by immunising Armenian hamsters with mouse BTLA/CD272:Fc fusion protein.

Specificity

This antibody is specific for B and T lymphocyte attenuator (BTLA), which functions as a negative regulator of T cell activation and proliferation, and attenuates B cell proliferation upon associating with its known ligand, herpes virus entry mediator (HVEM).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for BTLA/CD272 Antibody (HMBT-6B2) [Alexa Fluor® 594]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunoblotting

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BTLA

BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 (MIM 600244) and CTLA4 (MIM 123890), BTLA interacts with a B7 homolog, B7H4.[supplied by OMIM]

Long Name

B- And T-Lymphocyte Attenuator

Alternate Names

CD272

Gene Symbol

BTLA

Additional BTLA Products

Product Documents for BTLA/CD272 Antibody (HMBT-6B2) [Alexa Fluor® 594]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BTLA/CD272 Antibody (HMBT-6B2) [Alexa Fluor® 594]



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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