Butyrylcholinesterase/BCHE Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-69541

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Butyrylcholinesterase/BCHE Antibodies »

Product Summary for Butyrylcholinesterase/BCHE Antibody

Immunogen

Synthetic peptides corresponding to BCHE(butyrylcholinesterase) The peptide sequence was selected from the N terminal of BCHE. Peptide sequence SSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

68 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Butyrylcholinesterase/BCHE Antibody

Western Blot: Butyrylcholinesterase/BCHE Antibody [NBP1-69541]

Western Blot: Butyrylcholinesterase/BCHE Antibody [NBP1-69541]

Western Blot: Butyrylcholinesterase/BCHE Antibody [NBP1-69541] - This Anti-BCHE antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml.
Immunohistochemistry-Paraffin: Butyrylcholinesterase/BCHE Antibody [NBP1-69541]

Immunohistochemistry-Paraffin: Butyrylcholinesterase/BCHE Antibody [NBP1-69541]

Immunohistochemistry-Paraffin: Butyrylcholinesterase/BCHE Antibody [NBP1-69541] - Human Lung.

Applications for Butyrylcholinesterase/BCHE Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Butyrylcholinesterase/BCHE

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Alternate Names

Acylcholine acylhydrolase, BCHE, Butyrylcholine esterase, CHE1, Pseudocholinesterase

Gene Symbol

BCHE

UniProt

P06276

Additional Butyrylcholinesterase/BCHE Products

Product Documents for Butyrylcholinesterase/BCHE Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Butyrylcholinesterase/BCHE Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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