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C1QB Antibody (C1QB/2961) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79920

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C1QB/2961

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Summary for C1QB Antibody (C1QB/2961) - Azide and BSA Free

Immunogen

Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary) (Uniprot: P02746)

Localization

Cytoplasmic, Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-79786).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for C1QB Antibody (C1QB/2961) - Azide and BSA Free

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920]

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920]

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920] - Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with C1QB Mouse Monoclonal Antibody (C1QB/2961).
Protein Array: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920]

Protein Array: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920]

Protein Array: C1QB Antibody (C1QB/2961) - Azide and BSA Free [NBP2-79920] - Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (mAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb mAb of 14, then the S-score for the binding of that mAb to protein X is equal to 29.

Applications for C1QB Antibody (C1QB/2961) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: C1QB

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq]

Alternate Names

B chain, complement C1q subcomponent subunit B, complement component 1, q subcomponent, B chain, complement subcomponent C1q chain B, q subcomponent, beta polypeptide

Gene Symbol

C1QB

Additional C1QB Products

Product Documents for C1QB Antibody (C1QB/2961) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for C1QB Antibody (C1QB/2961) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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