C1qR1/CD93 Antibody (R139) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43378

Novus Biologicals, part of Bio-Techne
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NBP1-43378-25ug
NBP1-43378-0.1mg
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # R139

Format

BSA Free

Concentration

0.5 mg/ml

View all C1qR1/CD93 Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was CD93.

Reactivity Notes

This antibody is reactive to Human.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for C1qR1/CD93 Antibody (R139) - BSA Free

Flow Cytometry: C1qR1/CD93 Antibody (R139) - BSA Free [NBP1-43378]

Flow Cytometry: C1qR1/CD93 Antibody (R139) - BSA Free [NBP1-43378]

Flow Cytometry: C1qR1/CD93 Antibody (R139) [NBP1-43378] - Analysis using the Biotin conjugate of NBP1-43378. Staining of normal human peripheral blood cells with staining buffer (autofluorescence) (open histogram) or 0.5 ug of Anti-Human CD93 Biotin (filled histogram) followed by Streptavidin PE.

Applications for C1qR1/CD93 Antibody (R139) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
This R139 antibody has been tested by flow cytometric analysis of human peripheral blood cells. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.2)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: C1qR1/CD93

The monoclonal antibody R139 recognizes human CD93, also known as C1qRp. The glycoprotein CD93 binds to C1q, the subunit of the complement protein, mannose binding lectin and pulmonary surfactant protein A. CD93 is predicted to play a role in the clearance of apoptotic cells. Expression of CD93 is confined to myeloid cells with higher expression on monocytes than neutrophils, eosinophils, platelets and endothelial cells. Expression on DCs is downregulated upon maturation. Additionally, CD93 has been shown to define an early bone marrow stem cell population of hematopoietic and hepatic precursors. The monoclonal antibody R139 blocks C1q-mediated enhancement of phagocytosis. CD93 can be shed from the cell surface. This phenomenon can be measured using R3 antibody as detection with R139 as capture to detect soluble CD93 by ELISA. The epitope for R139 resides in the EGF domains.

Long Name

Complement Component C1q Receptor

Alternate Names

AA4 Antigen, C1q R1, C1q Rp, C1qRp, CD93, Collectin Receptor, Ly68

Gene Symbol

CD93

Additional C1qR1/CD93 Products

Product Documents for C1qR1/CD93 Antibody (R139) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for C1qR1/CD93 Antibody (R139) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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