CA125/MUC16 Antibody (CL2783)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59024

Novus Biologicals, part of Bio-Techne
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NBP2-59024
NBP2-59024-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL2783

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CA125/MUC16 Antibodies »

Product Summary for CA125/MUC16 Antibody (CL2783)

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence:GVLVTTRRRKKEGEYNVQQQCPGYYQSHLDLEDLQ

Epitope

NVQQQCPGYYQSHLD

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for CA125/MUC16 Antibody (CL2783)

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody [NBP2-59024] - Staining of human tonsil shows absence of immunoreactivity as expected (negative control).
Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody [NBP2-59024] - Staining of human endometrium shows strong immunoreactivity in apical membranes of glandular cells.
Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (CL2783) [NBP2-59024]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody [NBP2-59024] - Staining of human fallopian tube shows positivity in ciliated glandular cells.

Applications for CA125/MUC16 Antibody (CL2783)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CA125/MUC16

MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.

Long Name

Ovarian Cancer Antigen CA125

Alternate Names

MUC16

Gene Symbol

MUC16

UniProt

Q8WXI7

Additional CA125/MUC16 Products

Product Documents for CA125/MUC16 Antibody (CL2783)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CA125/MUC16 Antibody (CL2783)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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