CACNA2D1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60951

Novus Biologicals, part of Bio-Techne
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NB100-60951
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CACNA2D1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QEIFNKYNKDKKVR corresponding to internal region according to NP_000713.2.

Epitope

QEIFNKYNKDKKVR

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

125 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CACNA2D1 Antibody

Western Blot: CACNA2D1 Antibody [NB100-60951]

Western Blot: CACNA2D1 Antibody [NB100-60951]

Western Blot: CACNA2D1 Antibody [NB100-60951] - Staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for CACNA2D1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.03 - 0.1 ug/ml
Application Notes
WB: Approx. 140 kDa band observed in human brain (cerebellum) lysates (calculated MW of 123 kDa band according to NP_000713.2). An anonymous customer has reported it not suitable on mouse and rat protein.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CACNA2D1

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Long Name

Voltage-dependent calcium channel subunit alpha-2/delta-1

Alternate Names

CACNL2A, CCHL2A, MHS3

Entrez Gene IDs

781 (Human); 12293 (Mouse); 25399 (Rat)

Gene Symbol

CACNA2D1

UniProt

P54289 (Human)

Additional CACNA2D1 Products

Product Documents for CACNA2D1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CACNA2D1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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