CACNB4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30833

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CACNB4 Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from the rat CACNB4 conjugated to KLH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CACNB4 Antibody

CACNB4 Antibody

Western Blot: CACNB4 Antibody [NBP3-30833] -

Western Blot: CACNB4 Antibody [NBP3-30833] - Western blot analysis using beta4 antibody on rat brain lysate

Applications for CACNB4 Antibody

Application
Recommended Usage

Western Blot

: 5-10 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CACNB4

CACNB4 encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Long Name

Voltage-dependent L-type calcium channel subunit beta-4

Alternate Names

CAB4, CACNLB4

Gene Symbol

CACNB4

Additional CACNB4 Products

Product Documents for CACNB4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CACNB4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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