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Cadherin-6/KCAD Antibody (SR1127)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21896

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21896-100ul
NBP3-21896-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1127

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Cadherin-6/KCAD Antibody (SR1127)

Immunogen

A synthesized peptide derived from human Cadherin-6/KCAD (Uniprot #: P55285)

Specificity

Detects endogenous levels of total Cadherin-6/KCAD

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

130 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cadherin-6/KCAD Antibody (SR1127)

Western Blot: Cadherin-6/KCAD Antibody (SR1127) [NBP3-21896] -

Western Blot: Cadherin-6/KCAD Antibody (SR1127) [NBP3-21896] - Western blot analysis using NBP3-21896 in (1) Jurkat cell lysate; (2) Mouse heart lysate.

Applications for Cadherin-6/KCAD Antibody (SR1127)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin-6/KCAD

K Cadherin encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Alternate Names

Cadherin6, CDH6, K-Cadherin

Gene Symbol

CDH6

Additional Cadherin-6/KCAD Products

Product Documents for Cadherin-6/KCAD Antibody (SR1127)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cadherin-6/KCAD Antibody (SR1127)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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