Cadherin-6/KCAD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90347

Novus Biologicals, part of Bio-Techne
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NBP1-90347
NBP1-90347-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cadherin-6/KCAD Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cadherin-6/KCAD Antibody

Western Blot: Cadherin-6/KCAD Antibody [NBP1-90347]

Western Blot: Cadherin-6/KCAD Antibody [NBP1-90347]

Western Blot: Cadherin-6/KCAD Antibody [NBP1-90347] - Analysis in human cell line EFO-21.
Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347] - Staining of human fallopian tube shows moderate membranous and cytoplasmic positivity in cells in glandular cells.
Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-90347] - Staining of human kidney shows strong membranous positivity in cells in tubules.
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Applications for Cadherin-6/KCAD Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 3 using NBP1-90347 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin-6/KCAD

K Cadherin encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Alternate Names

Cadherin6, CDH6, K-Cadherin

Gene Symbol

CDH6

Additional Cadherin-6/KCAD Products

Product Documents for Cadherin-6/KCAD Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cadherin-6/KCAD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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