CADPS Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77323

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CADPS Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human CAPS1. The immunogen is located within the last 50 amino acids of CAPS1. Amino Acid Squence: DSTLNSKTYETIRNRLTVEE

Specificity

Numerous isoforms of CAPS1 are known to exist; the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CADPS Antibody - BSA Free

Western Blot: CADPS AntibodyBSA Free [NBP1-77323]

Western Blot: CADPS AntibodyBSA Free [NBP1-77323]

Western Blot: CADPS Antibody [NBP1-77323] - Rat brain tissue lysate with CADPS antibody at (A) 0.5 and (B) 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: CADPS Antibody - BSA Free [NBP1-77323]

Immunocytochemistry/ Immunofluorescence: CADPS Antibody - BSA Free [NBP1-77323]

Immunocytochemistry/Immunofluorescence: CADPS Antibody [NBP1-77323] - Immunofluorescence of CAPS1 in human brain tissue with CAPS1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: CADPS Antibody - BSA Free [NBP1-77323]

Immunohistochemistry-Paraffin: CADPS Antibody - BSA Free [NBP1-77323]

Immunohistochemistry-Paraffin: CADPS Antibody [NBP1-77323] - Human brain with CADPS antibody at 5 ug/ml.

Applications for CADPS Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CADPS

CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist; the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

Alternate Names

Ca++-dependent secretion activator, CADPS1, Calcium-dependent activator protein for secretion 1, calcium-dependent secretion activator 1, CAPS-1, CAPS1Ca2+-dependent secretion activator, CAPSCa2+-dependent activator protein for secretion, KIAA1121Ca2+-regulated cytoskeletal protein

Gene Symbol

CADPS

UniProt

NP_899631 (Human)

Additional CADPS Products

Product Documents for CADPS Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CADPS Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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