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CADPS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38871

Novus Biologicals, part of Bio-Techne
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NBP2-38871
NBP2-38871-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CADPS Antibody

Immunocytochemistry/ Immunofluorescence: CADPS Antibody [NBP2-38871]

Immunocytochemistry/ Immunofluorescence: CADPS Antibody [NBP2-38871]

Immunocytochemistry/Immunofluorescence: CADPS Antibody [NBP2-38871] - Staining of human cell line SK-MEL-30 shows localization to vesicles.
Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871]

Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871]

Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human kidney shows low expression as expected.
Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871]

Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871]

Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human pancreas shows strong cytoplasmic positivity in islets of Langerhans and subset of exocrine glandular cells.

Applications for CADPS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CADPS

CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq]

Alternate Names

Ca++-dependent secretion activator, CADPS1, Calcium-dependent activator protein for secretion 1, calcium-dependent secretion activator 1, CAPS-1, CAPS1Ca2+-dependent secretion activator, CAPSCa2+-dependent activator protein for secretion, KIAA1121Ca2+-regulated cytoskeletal protein

Gene Symbol

CADPS

UniProt

Additional CADPS Products

Product Documents for CADPS Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CADPS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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